Healthcare News
Ankles may hold the key to new osteoarthritis therapy
The ankle’s ability to regenerate cartilage uses the same mechanisms that enable some animals to grow new limbs, and it could be harnessed to repair cartilage in knees and hips hobbled by osteoarthritis
XSTEM’s Knee Osteoarthritis Stem Cell Trial: Mid-Study Update, Safety and Positive Efficacy
Xintela has released interim data from its ongoing clinical study evaluating its stem cell product, XSTEM, in patients with knee osteoarthritis. XSTEM is an allogeneic adipose stem cell therapy, consisting of integrin α10β1-selected mesenchymal stem cells. At 18 months post-treatment, the company reports demonstrated safety and positive efficacy, including statistically significant and clinically meaningful improvements in knee pain and knee function.
8 Types of Shoulder Surgeries
Common types of shoulder surgeries include rotator cuff repair, total shoulder replacement, and arthroscopy for conditions like frozen shoulder or impingement syndrome. In general, these and other shoulder procedures help treat shoulder injuries by repairing or replacing cartilage, tendons and ligaments, muscles, and joints.
Does running ruin your knees? And how old is too old to start?
You've probably heard that running is tough on your knees - and even that it can cause long-term damage. But is this true?
Understanding the differences between mobility and flexibility
Mobility and flexibility are related but distinct. Improving flexibility and mobility may improve a person’s athletic performance and range of motion, and help to reduce the risk of injuries.
8 Tips for Healthy Bones
It’s a fact of life: As you age, your bones become thinner and lose their density. Fortunately, you can take steps early on to strengthen your bone health and prevent osteopenia (bone thinning) and osteoporosis (late-stage bone loss). Bone health starts with proper nutrition, exercise and healthy lifestyle choices.
Synovial fluid protein levels may predict osteochondral allograft transplantation outcomes
Elevated levels of synovial fluid proteins may be associated with poor outcomes after osteochondral allograft transplantation. Synovial fluid protein levels may be used as a biomarker to predict outcomes.
Lubricated injectable electroactive short fibers facilitate cartilage repair through piezoelectric conversion
Precise repair of articular cartilage relies not only on the reconstruction of the extracellular matrix (ECM), but also on the restoration of its lubricating properties.
Stem Cell Therapies for Spinal Cord Injury in Humans: A Review of Recent Clinical Research
Recently, cell transplantation has emerged as a promising treatment for spinal cord injury (SCI). Over the past decade, numerous clinical studies of SCI have been conducted using various types of cells, including fetal neural stem/progenitor cells (NS/PCs), pluripotent stem cell-derived NS/PCs, mesenchymal stem/stromal cells (MSCs), olfactory ensheathing cells, and Schwann cells. Promising results have been reported for patients with subacute SCI, especially in studies involving MSCs, such as those conducted with Stemirac, although no universally recognized breakthroughs have been achieved. Allogenic NS/PCs may offer advantages over autologous MSCs because they have the potential for cell engraftment within the spinal cord and can be prepared in advance, facilitating their administration during the hyperacute phase.
Over-the-top triangular fibrocartilage complex repair may be viable option for instability
The triangular fibrocartilage complex is a critical structure in the wrist that provides stability to the distal radioulnar joint. Injury to the foveal attachment of the triangular fibrocartilage complex (TFCC) at the distal ulnar head often disrupts the deep fibers of the dorsal and volar radioulnar ligaments, leading to pain with or without distal radioulnar joint (DRUJ) instability. This article describes the arthroscopic inside-out transosseous or "over-the-top" technique to repair the TFCC and presents a case example of this method.
